It not only decreased the total serum bilirubin level after 3day, 5day, 7day treatment, but also decreased time of jaundice fading, as well as the duration of phototherapy and hospitalization, when compared with the control group. Probiotics supplementation treatment showed efficacy in neonatal jaundice. Results: 13 RCTs involving 1067 neonatal with jaundice were included in the meta-analysis. The relative risks (RR) or mean difference (MD) with a 95% confidence interval (CI) was used to measure the effect. The main outcomes of the trials were analyzed by Review Manager 5.3 software. The extracted information of RCTs should include efficacy rate, serum total bilirubin level, time of jaundice fading, duration of phototherapy, duration of hospitalization, adverse reactions. The cochrane tool was applied to assessing the risk of bias of the trials. Randomized controlled trials (RCTs) of probiotics supplementation for pathological neonatal jaundice in publications were extracted by two reviewers. Methods: Databases including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wan Fang Database (Wan Fang), Chinese Biomedical Literature Database (CBM), VIP Database for Chinese Technical Periodicals (VIP) were searched and the deadline is December 2016. Therefore, this study aims at systematically evaluating the efficacy and safety of probiotics supplement therapy for pathological neonatal jaundice. However, there is limited evidence regarding the effect of probiotics on bilirubin level in neonates. Probiotics supplementation therapy could assist to improve the recovery of neonatal jaundice, through enhancing immunity mainly by regulating bacterial colonies.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |